Early diagnosis and referral are associated with better clinical outcomes, however the time from symptom onset to diagnosis is often greater than 2 years ( 4– 6). Pulmonary hypertension (PH) is an insidious, highly morbid, and heterogeneous disease that is characterized by elevations in pulmonary arterial pressures and is classified into five groups based on etiology ( 1– 3). New non-invasive imaging techniques such as strain imaging, 3D echocardiography, dual energy CT, and 4D flow MRI are emerging techniques that can assist in the diagnosis and monitoring of pulmonary hypertension.Echocardiography, computed tomography, nuclear imaging, and magnetic resonance imaging are non-invasive imaging studies for screening, classification, prognostication, and monitoring of pulmonary hypertension.Pulmonary hypertension is a devastating disease and early detection improves morbidity and mortality.In this review, we will describe the utility and clinical application of multimodality imaging techniques across PH subtypes as it pertains to screening and monitoring of PH. Additionally, novel imaging modalities such as echocardiographic strain imaging, 3D echocardiography, dual energy CT, FDG-PET, and 4D flow MRI are actively being investigated to assess the severity of right ventricular dysfunction in PH. Multimodality imaging, including non-invasive modalities such as echocardiography, computed tomography, ventilation perfusion scans, and cardiac magnetic resonance imaging, has emerged as an integral tool for screening, classifying, prognosticating, and monitoring response to therapy in PH. Early identification of pulmonary vascular disease offers the opportunity to improve outcomes by instituting therapies that slow, reverse, or potentially prevent this devastating disease. The definitive diagnosis of PH is based upon hemodynamics measured by right heart catheterization however this is an invasive and resource intense study.

For resting PH to develop, ~50–70% of the pulmonary vasculature must be affected, suggesting that even mild hemodynamic abnormalities are representative of advanced pulmonary vascular disease. Pulmonary hypertension (PH) is a clinical condition characterized by progressive elevations in mean pulmonary artery pressures and right ventricular dysfunction, associated with significant morbidity and mortality. 4Division of Radiology, Johns Hopkins University, Baltimore, MD, United States.3Division of Cardiology, Johns Hopkins University, Baltimore, MD, United States.2Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, United States.1Division of Medicine, Johns Hopkins University, Baltimore, MD, United States.Hays 3 Steven Hsu 3 Steven Rowe 4 Stefan L. Christine Farrell 1 † Aparna Balasubramanian 2 † Allison G.

Steinberg diagnostic medical imaging